Gestational Thyrotoxicosis, Antithyroid Drug Use and Neonatal Outcomes Within an Integrated Healthcare Delivery System
Published in Thyroid
Incidence, Etiology, and Outcomes of Hazardous Hyperbilirubinemia in Newborns
Published in PEDIATRICS
Total serum bilirubin (TSB) levels ≥ 30 mg/dL are rare but potentially hazardous. A better understanding of their incidence, causes, and outcomes could help inform preventive efforts. We identified infants born ≥ 35 weeks' gestational age from 1995-2011 in Kaiser Permanente Northern California (n = 525409) and examined the medical records of infant...
Relationship Between Discharge Practices and Intensive Care Unit In-Hospital Mortality Performance
Published in Medical Care
Current intensive care unit performance measures include in-hospital mortality after intensive care unit admission. This measure does not account for deaths occurring after transfer to another hospital or soon after discharge and therefore, may be biased. Determine how transfer rates to other acute care hospitals and early post-discharge mortality ...
Adherence to Immunoprophylaxis Regimens for Respiratory Syncytial Virus Infection in Insured and Medicaid Populations
Published in Journal of the Pediatric Infectious Diseases Society
Immunoprophylaxis is the only pharmaceutical intervention for mitigating respiratory syncytial virus (RSV) infection. Patient level data on adherence to American Academy of Pediatrics (AAP) immunoprophylaxis recommendations are limited. This study characterizes adherence to AAP guidelines in privately insured and Medicaid populations
Comparison of vein valve function following pharmacomechanical thrombolysis versus simple catheter-directed thrombolysis...
Published in Journal of Vascular Surgery
Successful catheter-directed thrombolysis (CDT) for iliofemoral deep vein thrombosis (IFDVT) reduces post-thrombotic morbidity and is a suggested treatment option by the American College of Chest Physicians for patients with IFDVT. Pharmacomechanical thrombolysis (PMT) is also suggested to shorten treatment time and reduce the dose of plasminogen a...
The effect of race and ethnicity on outcomes among patients in the intensive care unit: A comprehensive study involving ...
Published in Critical Care Medicine
We sought to determine whether race or ethnicity is independently associated with mortality or intensive care unit length of stay among critically ill patients after accounting for patients' clinical and demographic characteristics including socioeconomic status and resuscitation preferences. Historical cohort study of patients hospitalized in inte...
Impact of Universal Bilirubin Screening on Severe Hyperbilirubinemia and Phototherapy Use
Published in PEDIATRICS
The goal was to assess the impact of universal bilirubin screening on severe hyperbilirubinemia and phototherapy use. In this retrospective cohort study of 358086 infants of > or =35 weeks and > or =2000 g born between January 1, 1995, and June 30, 2007, we obtained demographic data, bilirubin levels, and codes for inpatient phototherapy from exist...
Neonatal Neurocritical Care Service Is Associated With Decreased Administration of Seizure Medication
Published in Journal of Child Neurology
This cohort study examines medication use in term neonates with hypoxic-ischemic encephalopathy and seizures before and after implementation of a Neonatal Neurocritical Care Service (N = 108), which included increased seizure monitoring. Nearly all neonates received phenobarbital (96% pre- vs 95% post-Neonatal Neurocritical Care Service) and total ...
Numbers Needed to Treat With Phototherapy According to American Academy of Pediatrics Guidelines
Published in PEDIATRICS
Our aims were to estimate the efficacy of hospital phototherapy for neonatal jaundice and the number needed to treat to prevent one infant from reaching the exchange transfusion level. From a cohort of 281 898 infants weighing > or =2000 g born at > or =35 weeks' gestation at 12 Northern California Kaiser hospitals from 1995 to 2004, we identified ...
Stratification of Risk of Early-Onset Sepsis in Newborns >=34 Weeks' Gestation
...Published in PEDIATRICS
To define a quantitative stratification algorithm for the risk of early-onset sepsis (EOS) in newborns ≥ 34 weeks' gestation. We conducted a retrospective nested case-control study that used split validation. Data collected on each infant included sepsis risk at birth based on objective maternal factors, demographics, specific clinical milestones, ...
