Kaiser Permanente Northern California Perinatal Research Unit
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Impact of Universal Bilirubin Screening on Severe Hyperbilirubinemia and Phototherapy Use

Published in PEDIATRICS

The goal was to assess the impact of universal bilirubin screening on severe hyperbilirubinemia and phototherapy use. In this retrospective cohort study of 358086 infants of > or =35 weeks and > or =2000 g born between January 1, 1995, and June 30, 2007, we obtained demographic data, bilirubin levels, and codes for inpatient phototherapy from exist...

Numbers Needed to Treat With Phototherapy According to American Academy of Pediatrics Guidelines

Published in PEDIATRICS

Our aims were to estimate the efficacy of hospital phototherapy for neonatal jaundice and the number needed to treat to prevent one infant from reaching the exchange transfusion level. From a cohort of 281 898 infants weighing > or =2000 g born at > or =35 weeks' gestation at 12 Northern California Kaiser hospitals from 1995 to 2004, we identified ...

Stratification of risk of early-onset sepsis in newborns ≥ 34 weeks' gestation.

Escobar, Gabriel J Puopolo, Karen M Wi, Soora Turk, Benjamin J Kuzniewicz, Michael W Walsh, Eileen M Newman, Thomas B Zupancic, John Lieberman, Ellice Draper, David ...

Published in Pediatrics

To define a quantitative stratification algorithm for the risk of early-onset sepsis (EOS) in newborns ≥ 34 weeks' gestation. We conducted a retrospective nested case-control study that used split validation. Data collected on each infant included sepsis risk at birth based on objective maternal factors, demographics, specific clinical milestones, ...

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